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US 7,297,339 B2Granted
Rhodococcus equi mutants and vaccines comprising same
AssigneePresidents and Fellows of Harvard College
InventorsMary Hondalus, Shruti Jain, Joseph Ashour
Life of this patent
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Abstract
Mutant strains of Rhodococcus equi are disclosed, and vaccines comprising same.
Claims6
A mutant strain of Rhodococcus equi (R. equi), said mutant strain being a riboflavin auxotroph, and said mutant strain further having reduced pathogenicity relative to a wild type strain.
A method of making a genetically stable mutant R. equi strain, said method comprising inserting a transposon into the gene that encodes DHBP synthase.
Dependencies are inferred from the claim text.