Chlorogenic acid and an analog thereof for immune system stimulation
AssigneeN.V. Nutricia
InventorsYvo Maria Franciscus Graus, Hobbe Friso Smit, Albertus Dominicus Marcellinus Erasmus Osterhaus, Robert Johan Joseph Hageman
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Abstract
The present invention relates to a preparation for stimulating or enhancing an immune system comprising one or more agents that stimulate T-lymphocytes in vivo. Such a preparation can be sued in the prophylaxis and/or treatment of a medical condition. The invention further relates to a preparation for use in a pharmaceutical or food product and to a preparation for medical use.
Claims27
A preparation for stimulating or enhancing an immune system, comprising a liquid food product or a drink comprising zinc, at least one agent selected from the group consisting of chlorogenic acid and functional analogs thereof, said agent stimulating T-lymphocytes in vivo, and at least one polysaccharide selected from the group consisting of β-1,3-glucans, arabinogalactans, and polysaccharides that induce interferon production which are isolated from Echinacea species, Thuja occidentalis, Panax ginseng, Aranica montana cell cultures, Plantago spp, Achyrocline satureioides, Aconitum officinalis, Angelica acutiloba, Aristolochia officinalis, Astralagus gummerifa, A. membranaceus, A. mongholicus, Avena sativa, Banbusa vulgaris, Baptista tinctoria, Bryonia dioica, Calendula officinalis, Carthamus tinctorius, Chamomilla recutita, Echinacea angustifolia, E. pallida, E. purpurea, Eleutherococcus senticosus, Eupatorium cannabrinum, Silene vulgaris, Triticum sativum, Vincetoxicum officinalis, and Viscum album,
- wherein the weight to weight ratio of chlorogenic acid and functional analogs thereof to zinc is in the range of 0.0025 to 500.
A food product or drink for stimulating or enhancing an immune system, comprising 1-200 mg of zinc, 0.5-500 mg of at least one agent selected from the group consisting of chlorogenic acid and functional analogs thereof, said agent stimulating T-lymphocytes in vivo, and at least one polysaccharide selected from the group consisting of β-1,3-glucans, arabinogalactans, and polysaccharides that induce interfereon production which are isolated from Echinacea species, Thuja occidentalis, Panax ginseng, Aranica montana cell cultures, Plantago spp, Achyrocline satureioides, Aconitum officinalis, Angelica acutiloba, Aristolochia officinalis, Astralagus gummerifa, A. membranaceus, A. mongholicus, Avena sativa, Banbusa vulgaris, Baptista tinctoria, Bryonia dioica, Calendula officinalis, Carthamus tinctorius, Chamomilla recutita, Echinacea angustifolia, E. pallida, E. purpurea, Eleutherococcus senticosus, Eupatorium cannabrinum, Silene vulgaris, Triticum sativum, Vincetoxicum officinalis, and Viscum album,
- wherein the food product or drink is a liquid.
Dependencies are inferred from the claim text.