Vitreoretinal silicone tamponades made by supercritical fluid extraction
AssigneeBausch & Lomb Incorporated
InventorsJay F. Kunzler, Joseph C. Salamone, Dharmendra Jani, Erik M. Indra
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Abstract
A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.
Claims13
A method of using a tamponade in an ophthalmic surgical procedure comprising:
- creating an incision into a posterior chamber of an eye;
- and
- filling said posterior chamber of the eye with said tamponade consisting essentially of a silicone oil that was purified by supereritical carbon dioxide extraction to remove cyclic and oligomeric impurities.
A method of using a tamponade in an ophthalmic surgical procedure comprising:
- creating an incision into a posterior chamber of an eye;
- and
- filling said posterior chamber of the eye with said tamponade consisting essentially of a silicone oil that was purified with a mixture comprising carbon dioxide under supercritical extraction conditions to remove cyclic and oligomeric impurities.
Dependencies are inferred from the claim text.