Purification and uses of dendritic cells and monocytes
AssigneeCenter of Blood Research
InventorsKeith D. Crawford, Chester A. Alper
Life of this patent
Estimating the term…
Abstract
Methods for the preparation of substantially purified populations of dendritic cells and monocytes from the peripheral blood of a mammal is described. Also described are vaccine compositions and methods for the treatment of certain diseases and medical conditions based on the substantially purified dendritic cells and monocytes.
Claims7
A substantially purified population of mammalian dendritic cells wherein said dendritic cells express antigen CD14 and antigen CD2.
A method for stimulating the production of IL-12 in vivo in a mammal comprising administering a population of substantially purified dendritic cells to the mammal, said dendritic cells expressing CD14 and CD2 antigens, wherein said dendritic cells have been activated by ligation with at least one anti-CD2 antibody.
Dependencies are inferred from the claim text.