Rapid diagnostic method for detecting bacterial sinusitis
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsParker Small, Shih-Wen Huang
Life of this patent
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Abstract
A method and device for rapidly, non-invasively and inexpensively differentiating between allergic rhinitis, upper respiratory tract viral infection and bacterial sinusitis, comprising a support strip upon which is fixed discrete indicators of pH, protein content, nitrite content, esterase activity, and eosinophil content of a sample with which said reagent test strip is contacted. Contact of a nasal secretion with the device of this invention permits differentiation between allergic, bacterial and viral conditions, based on pH, protein content, esterase activity, nitrite content, and eosinophil content.
Claims1
A method for detecting bacterial sinusitis, said method comprising obtaining a nasal secretion sample from a patient;
- and measuring said nasal secretion sample for pH, protein content, nitrite content, and leukocyte esterase activity;
- wherein a pH between 7.5 and 9, and a protein content of at least 100 mg/dL, a presence of nitrite and a presence of leukocyte esterase activity is indicative of bacterial sinusitis.
Dependencies are inferred from the claim text.