Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein

An interstitial fluid (ISF) extraction device comprising:

• a penetration member configured for penetrating a target site of a user's skin layer and, subsequently, residing in the user's skin layer and extracting an ISF sample therefrom;
• and
• at least three concentrically-arranged pressure rings, each of the at least three concentrically-arranged pressure rings adapted for applying pressure to the user's skin layer in the vicinity of the target site while the penetration member is residing in the user's skin layer,
• wherein the ISF extraction device is configured such that the at least three concentrically-arranged pressure rings apply pressure in an oscillating manner with asymmetric deployment and retraction cycle timing, and
• wherein only one of the at least three concentrically-arranged pressure rings is deployed at a time, whereby an ISF glucose lag of the ISF sample extracted by the penetration member is mitigated.