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US 7,257,437 B2Granted
Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
AssigneeThe Regents of the University of California
InventorsStavros G. Demos, Ralph W. deVere White
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Abstract
Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and/or tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.
Claims13
A diagnostic apparatus, comprising:
- at least two substantially narrow-band electro-magnetic radiation wavelength sources directed to illuminate one or more tissue components,
- an interior examination device adapted to transmit the wavelength sources for illumination of the tissue components and further adapted to relay a near-infrared scattered radiation of the illuminated tissue components,
- a detector adapted to simultaneously capture images produced by the near-infrared scattered radiation from the tissue components;
- and
- means to characterize the captured near-infrared scattered radiation from the tissue components.
2 more elements
A diagnostic apparatus, comprising:
- at least two laser sources directed to illuminate one or more tissue components,
- a cystoscope adapted to transmit the laser sources for illumination of the tissue components and further adapted to relay a scattered near-infrared radiation produced by the illuminated tissue components,
- a two-dimensional CCD, adapted to simultaneously capture images produced by the scattered near-infrared radiation from the tissue components;
- and
- a computer configured with an image processing software to characterize the captured near-infrared scattered radiation from the tissue components.
2 more elements
Dependencies are inferred from the claim text.