Method for imaging biological matter using an adiabatic pulse
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorRohit Sood
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Abstract
The present invention includes a method for MR imaging of a biological matter having H2O17 content by performing T1ρoff imaging of said H2O17 content in said biological matter. The T1ρoff imaging is performed by applying an RF pulse with a resonance frequency offset to said biological matter to create off resonance spin locking conditions in said biological matter. Thus, parts of the biological matter having different H2O17 concentrations are differentiated because of their different T2/T1 ratios.
Claims20
A method for MR imaging of a biological matter having H2O17 content, comprising:
- applying an adiabatic RF pulse with a resonance frequency offset to said biological matter;
- and
- performing T1ρoff imaging of said H2O17 content in said biological matter.
A method of imaging a biological matter to differentiate parts of said biological matter having different concentrations of a particular compound, comprising:
- placing said biological matter in a static magnetic field along a first direction;
- and
- applying an adiabatic RF pulse to said biological matter to create an effective magnetic field of a tissue spin system in a second direction, wherein an angle between said first and second directions is substantially near 0°.
A method of MR imaging of a patient, comprising:
- administering H2O containing O17 to said patient;
- and
- applying an adiabatic RF pulse to said patient, wherein said RF pulse has a resonance frequency offset less than about 1000 Hz, and wherein said RF pulse creates substantial contrast between image signals from parts of said patient having different O17 concentrations.
Dependencies are inferred from the claim text.