Levalbuterol salt
AssigneeSepracor Inc.
InventorsPaul McGlynn, Roger Bakale, Craig Sturge
Life of this patent
Estimating the term…
Abstract
Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
Claims29
Levalbuterol L-tartrate.
An aerosol formulation adapted for administration using a metered dose inhaler, the aerosol formulation comprising levalbuterol L-tartrate crystals in the form of micronized, needle-like particles, and a propellant.
A process for the preparation of levalbuterol L-tartrate crystals, which comprises combining a solution of levalbuterol with a solution of L-tartaric acid and recovering levalbuterol L-tartrate crystals.
A process for the preparation of levalbuterol L-tartrate crystals, which comprises combining a solution of levalbuterol with a solution of L-tartaric acid, recovering levalbuterol L-tartrate crystals, and then drying and micronizing the recovered crystals, the crystallization and drying conditions being selected so as to afford needle-like particles after micronization.
A method of effecting bronchodilation in a patient in need of treatment, which comprises administering to said patient an effective amount of levalbuterol L-tartrate.
Dependencies are inferred from the claim text.