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US 7,256,288 B2Granted
Heteroaryl carboxylic acid amides
AssigneeBayer HealthCare LLC
InventorsMartin Hendrix, Frank-Gerhard Böss, Christina Erb, Joachim Krüger, Joachim Luithle, Christoph Methfessel, Rudy Schreiber, Welf-Burkhard Wiese
Life of this patent
Estimating the term…
Abstract
The invention relates to novel heteroaryl carboxamides, a process for their preparation, and pharmaceutical compositions containing them. These materials are useful for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
Claims5
A compound of the formula (I)
- in which
- R1 is an azabicyclo[m.n.o]alkyl radical having 7 to 11 ring atoms, in which m, n and o are identical or different and are 0, 1, 2 or 3,
- and where the radical is optionally substituted by (C1-C6)-alkyl,
- the ring A is pyrimido, or
- is optionally benzo-fused pyrido, pyridazo or pyridazino,
- and
- R2 and R3 are identical or different and are radicals selected from the group of hydrogen, halogen, formyl, carbamoyl, cyano, trifluoromethyl, trifluoromethoxy, nitro, (C1-C6)-alkyl, (C1-C6)-alkoxy, (C1-C6)-alkylthio, (C3-C8)-cycloalkyl, 4- to 8-membered heterocyclyl, phenyl or 5- to 6-membered heteroaryl, where phenyl and heteroaryl are optionally substituted by halogen, (C1-C4)-alkyl, (C1-C4)-alkoxy, amino, mono- or di-(C1-C4)-alkylamino, (C1-C4)-alkanoylamino or (C1-C4)-alkanesulfonylamino,
- or a salt thereof.
5 more elements
Dependencies are inferred from the claim text.