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US 7,256,209 B2Granted
Pyrazole derivatives and diabetic medicine containing them
AssigneeAjinomoto Co., Inc.
InventorsKoji Ohsumi, Takashi Umemura, Hiroyuki Matsueda, Toshihiro Hatanaka, Akiko Onuki, Katsumi Maezono, Yoko Kageyama, Nobuo Kondo
Life of this patent
Estimating the term…
Abstract
The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine
Claims17
A pyrazole compound of formula (1A) or (1B) or a pharmaceutically acceptable salt thereof:
- wherein X represents a hydrogen atom;
- Y represents a lower alkyl group or a perfluoro lower alkyl group;
- Z represents a hydrogen atom, a lower alkyl group, a perfluoro lower alkyl group, an aralkyl group or a phenyl group;
- R1, R2, R3, R4, and R5 may be the same or different and each represents a hydrogen atom, a lower alkyl group, a perfluoro lower alkyl group, a lower alkoxy group, a perfluoro lower alkoxy group, a lower alkylthio group, a perfluoro lower alkylthio group, a lower alkyl amino group, a halogeno atom, a lower alkanoyl group, a lower alkenyl group or a lower alkynyl group, and n represents an integer from 0 to 3,
- wherein at least two of R1, R2, R3, R4, and R5 independently represents a lower alkyl group, a perfluoro lower alkyl group, a lower alkoxy group, a perfluoro lower alkoxy group, a lower alkylthio group, a perfluoro lower alkylthio group, a lower alkyl amino group, a halogeno atom, a lower alkanoyl group, a lower alkenyl group or a lower alkynyl group.
2 more elements
A pyrazole compound of formula (1A) or (1B) or a pharmaceutically acceptable salt thereof:
- wherein X represents a hydrogen atom;
- Y represents a lower alkyl group or a perfluoro lower alkyl group;
- Z represents a hydrogen atom, a lower alkyl group, a perfluoro lower alkyl group, an aralkyl group or a phenyl group;
- R1, R2, R4, and R5 may be the same or different and each represents a hydrogen atom, a lower alkyl group, a perfluoro lower alkyl group, a lower alkoxy group, a perfluoro lower alkoxy group, a lower alkylthio group, a perfluoro lower alkylthio group, a lower alkyl amino group, a halogeno atom, a lower alkanoyl group, a lower alkenyl group or a lower alkynyl group;
- and n represents an integer from 0 to 3,
- wherein at least one of R1, R2, R4, and R5 represents a lower alkyl group having 1 to 6 carbon atoms, a lower alkylthio group having 1 to 6 carbon atoms, a halogeno atom, a lower alkoxy group, a lower alkenyl group, or a lower alkynyl group;
- and
- R3 represents a lower alkyl group having 1 to 6 carbon atoms, a lower alkylthio group having 1 to 6 carbon atoms, a halogeno atom, a lower alkoxy group, a lower alkenyl group, or a lower alkynyl group.
5 more elements
Dependencies are inferred from the claim text.