Diagnostic device for analyte detection
AssigneeNanogen, Inc.
InventorWei Hu
Life of this patent
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Abstract
The present invention provides a hand-held device of the type useful to perform an in vitro immunodiagnostic assay for an analyte of interest. In embodiments of the invention, the device incorporates a carrier for conducting the assay which comprises an array of pads including a sample pad, a narrow detection pad for detecting analyte, and a bridging pad coupled in flow communication therebetween. The device is provided with a housing adapted to deliver sample onto the carrier as a linear band having a width greater than the detection pad. In combination, these features yield a device that retains the sensitivity required for diagnostic accuracy, yet is improved in terms of cost and ease of manufacture.
Claims16
A device of the type useful to perform a lateral flow immunodiagnostic assay for one or more target analytes, the device comprising:
- (a) a carrier for conducting the flow of sample along a path, the carrier comprising:
- a sample receiving zone comprising a detectably labeled, mobile detector reagent for binding to the target analyte, and
- an analyte detection zone downstream of the sample receiving zone and comprising an immobilized capture reagent for capturing a complex formed by said analyte and said detector reagent, and
- (b) a housing for receiving the carrier, the housing comprising
- a sample receiving system and
- a sample deposition system in flow communication with the sample receiving system and the carrier, wherein the sample deposition system delivers sample from the sample receiving system onto the carrier as a sample band that is essentially linear and has a width greater than the width of the analyte detection zone, the width being transverse to the path of sample flow.
Dependencies are inferred from the claim text.