Reagent for determining laminin 5 antigen in biological sample and assay method
AssigneeEisai R&D Management Co., Ltd.
InventorsMasahiko Katayama, Noriko Sanzen, Kiyotoshi Sekiguchi
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Abstract
A method of determining a laminin 5 antigen in a biological sample, comprising the steps of bringing an antibody reactive to a laminin 5 γ2 chain N-terminal fragment into contact with the biological sample; measuring a reaction of the antibody; and determining an amount of the laminin 5 antigen based on a measurement result of the reaction, as well as, a method of detecting a laminin 5-producing tumor cell, a method of examining acute respiratory distress syndrome and a method of evaluating malignancy of a malignant tumor based on the assay method.
Claims2
A method of detecting a laminin 5-producing tumor cell by determining an amount of a laminin 5 antigen in a blood specimen, comprising the steps of:
- bringing an antibody reactive to a laminin 5 γ2 chain N-terminal fragment into contact with the blood specimen;
- measuring a reaction of the antibody;
- determining an amount of the laminin 5 antigen based on a measurement result of the reaction;
- and
- detecting a laminin 5-producing tumor cell based on the determined amount of the laminin 5 antigen, wherein if the determined amount is high compared with healthy persons, the laminin 5-producing tumor cell is detected.
Dependencies are inferred from the claim text.