Selecting animals for parentally imprinted traits
AssigneesMelica HB, University of Liege, SEGHERSgentec N.V.
InventorsLeif Andersson, Michel Georges, Geert Spincemaille, Carina Danielle A. Nezer
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Abstract
The invention relates to methods to select breeding animals or animals destined for slaughter for having desired genotypic or potential phenotypic properties, in particular related to muscle mass and/or fat deposition. The invention provides a method for selecting a pig for having desired genotypic or potential phenotypic properties comprising testing a sample from said pig for the presence of a quantitative trait locus (QTL) located at a Sus scrofa chromosome 2 mapping at position 2p1.7.
Claims1
A method for selecting a pig for breeding by identifying a pig having a paternally imprinted quantitative trait locus (QTL) associated with larger muscle mass and decreased fat deposition such that when the pig is used in a breeding program, the offspring of the pig that inherit said QTL from the male parent have larger muscle mass and decreased fat deposition compared to controls, wherein the method for selecting a pig comprises:
- identifying the presence of the paternally imprinted QTL associated with larger muscle mass and decreased fat deposit by detecting one or more genetic markers selected from the group consisting of genetic markers linked to the QTL on chromosome 2 of the pig, genetic markers in linkage disequilibrium with the paternally imprinted QTL on chromosome 2 of the pig, and combinations of any thereof;
- wherein the paternally imprinted QTL comprises the insulin-like growth factor-2 gene (IGF-2) as well as the genetic markers Swr2516, Swc9, Sw2623, and Swr783 on chromosome 2 of the pig;
- wherein the QTL is present on chromosome 2 of the pig at position 2p1.7;
- and
- wherein the identification of the pig having the paternally imprinted QTL associated with larger muscle mass and decreased fat deposit selects the pig for breeding.
Dependencies are inferred from the claim text.