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US 7,253,320 B2Granted
Process for preparing polymorphic form II of sertraline hydrochloride
AssigneeSandoz Ltd.
InventorsJohannes Ludescher, Josef Wieser
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Abstract
The present invention relates to a new process for preparing sertraline hydrochloride form II.
Claims9
A process for preparing sertraline hydrochloride form II comprising the steps of:
- a) providing a solution or suspension of sertraline base or a salt thereof in a suitable solvent;
- b) adding a hydrochloride of an organic amide at a temperature in the range of from about 0° C. to about 120° C., and
- c) isolating the crystalline solid polymorphic form II of sertraline hydrochloride.
Dependencies are inferred from the claim text.