Hexafluoroisopropanol substituted cyclohexane derivatives

A compound of formula (I)

• wherein
• R1 is hydrogen, lower-alkyl, fluoro-lower-alkyl, lower-alkyl-carbonyl, fluoro-lower-alkyl-carbonyl, aryl-lower-alkyl, cycloalkyl-lower-alkyl, cycloalkyl-carbonyl or cycloalkyl-lower-alkyl-carbonyl;
• R2 is hydrogen or lower-alkyl;
• R3 is lower-alkyl, aryl-lower-alkyl, heterocyclyl-lower-alkyl or lower-alkoxy-carbonyl, or, if X is not a single bond, or, if X is a single bond and m is not 0, R3 can also be hydroxy;
• R4 is aryl or heterocyclyl;
• X is a single bond, SO2, CO, C(O)O or C(O)N(R5);
• R5 is hydrogen, lower-alkyl, aryl, heterocyclyl, aryl-lower-alkyl or heterocyclyl-lower-alkyl;
• m is 0, 1, 2 or 3;
• n is 0 or 1;
• and pharmaceutically acceptable salts and esters thereof.