Purification process for manufacturing a high pure acarbose

#1. Field of the Invention

#The present invention relates to a process for manufacturing a highly pure acarbose, and particularly to a process which uses alcohol for precipitation and separation, and a strong cation exchange chromatography and an immobilized enzyme affinity chromatography for manufacturing a highly pure acarbose to treat diabetes.

#2. Description of the Related Art

#The present invention will become more fully understood from the detailed description given hereinbelow and the accompanying drawings which are given by way of illustration only, and thus are not limitative of the present invention, and wherein:

#FIG. 1 is a flow chart showing a purification process for manufacturing a highly pure acarbose of the present invention;

#FIG. 2 is flow chart showing a purification process for manufacturing a highly pure acarbose of Example 1 of the present invention;

#Refer to FIG. 1, the present invention discloses a purification process for manufacturing highly pure acarbose comprising the steps of:

#Step 10, start;

#Step 15, adding alcohol in an acarbose-containing fermentation broth for precipitation;