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US 7,253,209 B2Granted
Remedies for cisplatin-tolerant cancer
AssigneeDainippon Sumitomo Pharma Co., Ltd.
InventorsShuichi Kishimoto, Shoji Fukushima, Yoshikazu Takeuchi
Life of this patent
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Abstract
Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
Claims1
A method for promoting the uptake of a platinum complex into cisplatin-resistant hepatic cancer cells, which comprises administering a solution or suspension of cis-[((1R,2R)-1,2-cyclohexane-diamine-N,N′)bis(myristato)] platinum (II) of the formula:
- in an iodized poppyseed oil fatty acid ethyl ester to the hepatic artery of a subject having a cisplatin-resistant hepatic cancer.
Dependencies are inferred from the claim text.