Ancillary composition for the preparation of committed mature dentritic cells
AssigneeI.D.M. Immuno-Designed Molecules
InventorsClaire Boccaccio, Alessandra Nardin, Jean-Pierre Abastado
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Abstract
The invention consists in the use of a maturation agent comprising a mixture of ribosomal and/or membrane fractions for the preparation of mature dendritic cells from immature dendritic cells.
Claims20
A method for the preparation of mature dendritic cells from immature dendritic cells, comprising treating said immature dendritic cells with a maturation agent comprising a bacterial mixture of ribosomal fractions or ribosomal and membrane fractions to obtain mature dendritic cells.
A process for the preparation of mature dendritic cells from immature dendritic cells, said process comprising the step of contacting in a culture medium immature dendritic cells with a maturation agent comprising a bacterial mixture of ribosomal fractions or ribosomal and membrane fractions to obtain mature dendritic cells.
A method for the preparation of mature dendritic cells from immature dendritic cells, comprising treating said immature dendritic cells with a maturation agent comprising a bacterial mixture of ribosomal fractions or ribosomal and membrane fractions, and wherein the ribosomal fractions are from bacterial strains selected from the group consisting of Klebsiella pneumoniae, Streptococcus pneumoniae, Streptococcus pyogenes group A and Haemophilus influenzae to obtain mature dendritic cells.
Dependencies are inferred from the claim text.