Preparation of nanoparticles
AssigneeImperial College of Science, Technology and Medicine
InventorsAndrew De Mello, John De Mello, Joshua Edel
Life of this patent
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Abstract
The present invention provides a method and apparatus for the production of nanoparticles using a continuous flow miniaturised reaction vessel. In particular, the invention provides a method for preparing nanoparticles by a direct one-stage process.
Claims10
A method of producing crystalline nanoparticles using a continuous flow miniaturised reaction vessel, wherein the reaction vessel comprises at least one inlet, a reaction chamber and at least one outlet, the method comprising:
- supplying a continuous reactant flow to the reaction chamber via the inlet;
- controlling physical and chemical conditions in the reaction chamber so that reaction occurs to form crystalline nanoparticles of a pre-selected, defined dimension;
- and
- continuously extracting the formed crystalline nanoparticles from the reaction chamber via the outlet.
A miniaturised crystalline nanoparticle production device comprising:
- at least one inlet,
- a reaction chamber that receives a reactant flow sufficient to form crystalline nanoparticles;
- at least one outlet, and at least one of a temperature varying element that produces a temperature gradient across the reaction chamber so that the formed crystalline nanoparticles are of varying predetermined dimensions, an illumination element that produces an optical illumination intensity gradient across the reaction chamber so that the formed crystalline nanoparticles are of varying predetermined dimensions, and an inlet positioned to provide an off-center continuous reactant flow into the reaction chamber to produce a pH gradient and/or reactant concentration gradient across the reaction chamber so that the formed crystalline nanoparticles are of varying predetermined dimensions,
- wherein the device is ananged to allow the continuous reactant flow into the reaction chamber and to allow a continuous flow of formed crystalline nanoparticles out the outlet.
A miniaturised crystalline nanoparticle production device comprising:
- a reaction chamber;
- a first inlet for supply of at least one reactant adapted to form a crystalline nanoparticulate product to the reaction chamber;
- a first outlet for extraction of the crystalline nanoparticulate product from the reaction chamber;
- a second outlet for extraction of unreacted or partially reacted reactant from the reaction chamber;
- and
- a second inlet for recycling of the unreacted reactant or partially reacted reactant into the reaction chamber.
Dependencies are inferred from the claim text.