Back to results
US 7,252,720 B2Granted
Removal of prion infectivity
AssigneeCommon Services Agency
InventorsPeter Reynolds Foster, Brenda Doreen Griffin, Ronald Vance McIntosh
Life of this patent
Estimating the term…
Abstract
Prion infectivity adsorbed onto substrates (for example, chromatographic columns used to fractionate blood plasma) is removed by treatment with 2M sodium chloride. Optionally, the substrate is further washed with 0.1 M sodium hydroxide.
Claims10
A method of cleaning a substrate of chromatographic materials in order to remove adsorbed prion infectivity, comprising washing the substrate with a concentrated salt solution consisting of an aqueous solution of sodium chloride, having a concentration of at least 1.0 M.
Dependencies are inferred from the claim text.