Regulating metabolism by modifying the level of trehalose-6-phosphate
AssigneeSyngenta Mogen B.V.
InventorsOscar Johannes Maria Goddijn, Jan Pen, Josephus Christianus Maria Smeekens
Life of this patent
Estimating the term…
Abstract
Method for the inhibition of carbon flow in the glycolytic direction in a cell by increasing the intracellular availability of trehalose-6-phosphate.
Claims3
Method for the inhibition of carbon flow in the glycolytic direction in a plant cell by increasing the intracellular availability of trehalose-6-phosphate by transformation of said plant cell with a vector comprising a sequence encoding an antisense gene for trehalose-6-phosphate phosphatase (TPP) operably linked to a promoter in antisense orientation, which upon expression is able to inhibit functional activity of the endogenous trehalose-6-phosphate phosphatase (TPP) gene.
A cloning vector which comprises a sequence encoding an antisense gene for trehalose-6-phosphate phosphatase (TPP) operably linked to a promoter in antisense orientation, which upon expression is able to inhibit functional activity of the endogenous trehalose-6-phosphate phosphatase (TPP) gene in a plant cell.
Plant characterized in that it or one of its ancestors is transformed with a vector comprising a construct comprising a sequence encoding an antisense gene for trehalose-6-phosphate phosphatase (TPP) operably linked to a promoter in antisense orientation, which upon expression is able to inhibit functional activity of the endogenous trehalose-6-phosphate phosphatase (TPP) gene in a cell of said plant, said plant still containing said construct antisense gene.
Dependencies are inferred from the claim text.