Periocular drug delivery for diabetic retinopathy
AssigneeThe Penn State Research Foundation
InventorsThomas W. Gardner, Chad E. Reiter
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Abstract
This invention provides reagents and methods for delivering insulin, insulinomimetic agents, and the like to a vertebrate eye via subconjunctival routes, sub-Tenon's routes, or intravitreal routes for treatment of nerve-related vision disorders such as diabetic retinopathy, and formulations useful in the practice of the disclosed methods.
Claims18
A method of treating a nerve-related vision disorder in a diabetic subject comprising the step of administering a therapeutically effective amount of a formulation of insulin, to an eye affected by the nerve-related vision disorder via a periocular route, wherein the therapeutically effective amount is effective to achieve a local therapeutic effect without a substantial systemic effect.
Dependencies are inferred from the claim text.