Biocompatible polymeric compositions for use in making anterior chamber intraocular lenses
AssigneeAdvanced Medical Optics, Inc.
InventorsHarish C. Makker, Michael D. Lowery, Can B. Hu
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Abstract
Biocompatible polymers useful for making anterior chamber intraocular lenses (AC-IOL) are provided. The biocompatible polymers are generally composed of one or more acrylate monomers, crosslinked with at least one diacrylate ester and may include one or more additional components such as ultraviolet light and/or blue-violet light absorbing dyes. The AC-IOLs made using the biocompatible polymers disclosed herein are suitable for placement in phakic or aphakic eyes and are intended for refractive correction including myopia, hyperopia, presbyopia and astigmatisms.
Claims20
A biocompatible polymer comprising:
- 50 mass percent to 55 mass percent of a first alkyl acrylate,
- 29 mass percent to 32 mass percent of a second alkyl acrylate,
- 9 mass percent to 11 mass percent of a fluoroacrylate,
- 4 mass percent to 5 mass percent of a diacrylate ester crosslinking agent;
- wherein said biocompatible polymer is used to form an anterior chamber intraocular lens (AC-IOL).
The biocompatible polymer according to clam 1 wherein said first alkyl acrylate and said second alkyl acrylate are selected from the group consisting of, ethyl methacrylate, n-butyl acrylate, ethyl acrylate and 2-ethyl hexyl acrylate, providing that said first acrylate ester is different than said second acrylate ester.
A biocompatible polymer comprising:
- 50 mass percent to 55 mass percent of ethyl acrylate,
- 29 mass percent to 32 mass percent of ethyl methacrylate,
- 9 mass percent to 11 mass percent of trifluoroethyl methacrylate,
- 4 mass percent to 5 mass percent of ethylene glycol dimethacrylate;
- wherein said biocompatible polymer is used to form an anterior chamber intraocular lens (AC-IOL).
An AC-IOL comprising:
- 54 mass percent of ethyl acrylate,
- 30 mass percent of ethyl methacrylate,
- 10 mass percent of trifluoro methacrylate, and
- 5 mass percent of glycol dimethacrylate;
- wherein residual solvents and UV absorbing compounds make up the remaining mass percentage such the total mass percent is 100.
An AC-IOL consisting essentially of
- 54 mass percent of ethyl acrylate,
- 30 mass percent of ethyl methacrylate,
- 10 mass percent of trifluoro methacrylate, and
- 5 mass percent of glycol dimethacrylate;
- wherein residual solvents and UV absorbing compounds make up the remaining mass percentage such the total mass percent is 100.
A biocompatible polymer consisting essentially of
- 54 mass percent of ethyl acrylate,
- 30 mass percent of ethyl methacrylate,
- 10 mass percent of trifluoro methacrylate, and
- 5 mass percent of glycol dimethacrylate;
- wherein residual solvents and UV absorbing compounds make up the remaining mass percentage such the total mass percent is 100 mass percent;
- and wherein said biocompatible polymer is used to form an anterior chamber intraocular lens.
A biocompatible polymer comprising 50 mass percent to 55 mass percent of a first alkyl acrylate, 29 mass percent to 32 mass percent of a second alkyl acrylate, 9 mass percent to 11 mass percent of a fluoroacrylate, and 4 mass percent to 5 mass percent of a diacrylate ester crosslinking agent;
- wherein said biocompatible polymer has a Tg of approximately 17° C., a tensile strength of approximately 1690 psi;
- an elongation at break of approximately 110% and is used to form an anterior chamber intraocular lens (AC-IOL).
Dependencies are inferred from the claim text.