Pigment epithelial cell of the eye, its production and use in therapy of an eye or CNS disease
OwnerStefan Kochanek, Ulrich Schraermeyer +1inventors
InventorsStefan Kochanek, Ulrich Schraermeyer, Gabriele Thumann
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Abstract
The present invention relates to a pigment epithelial cell of the eye containing vector DNA of an adenoviral vector with large DNA capacity, to the improved isolation and cultivation of these cells and to methods for production and the use in the therapy of an eye or nerve disease.
Claims7
A method for producing a pigment epithelial cell of the eye comprising an adenoviral vector, the method comprising introducing an adenoviral vector to the pigment epithelial cell of the eye and cultivating the cell in serum-free medium and in the presence of a feeder layer, the adenoviral vector comprising at least one expressed nucleic acid operatively linked to a promoter, said vector comprising neither adenoviral nor E. coli coding DNA sequences.
Dependencies are inferred from the claim text.