Back to results
US 7,247,471 B2Granted
Spiral pleated roller bottle
AssigneeBecton, Dickinson and Company
InventorsAnne M. Kadar, Kenneth W. Whitley
Life of this patent
Estimating the term…
Abstract
A roller bottle is provided with a bottom wall, a top wall and a cylindrical side wall extending between the bottom and top walls. The top wall includes an opening to provide access to the interior of the roller bottle. The cylindrical side wall of the roller bottle is formed with at least one spiral pleat extending substantially from the bottom to the top for increasing cell growth surface area and for facilitating the flow of liquid to all interior surface areas of the bottle as the bottle is rolled about its longitudinal axis.
Claims13
A roller bottle for use in culturing cells, comprising:
- a bottom;
- a top;
- and,
- a continuous side wall extending between said bottom and said top, said side wall having an interior surface and an exterior surface, and being spaced about a longitudinal axis of said bottle for allowing said bottle to rotate along said side wall about the longitudinal axis for distributing, along said side wall, a liquid medium contained in said bottle to wet said side wall, said side wall including at least one pleat extending from a first point proximate said top to a first point proximate said bottom, said pleat being arranged at an angle offset with respect to a plane perpendicular to the longitudinal axis of said bottle, said pleat defining at least one interior channel on said inner surface of said side wall for permitting laminar flow and distribution of said liquid along said pleat, said interior channel providing a surface for culturing the cells, wherein at least one smooth land is formed in said side wall, said land interrupting said pleat.
1 more element
Dependencies are inferred from the claim text.