US 7,247,442 B1Granted

Antibodies to HHPEN62 polypeptide

AssigneeHuman Genome Sciences, Inc.

InventorsSteven M. Ruben, Kimberly A. Florence, Jian Ni, Craig A. Rosen, Kenneth C. Carter, Paul A. Moore, Henrik S. Olsen, Yanggu Shi, Paul E. Young, Ying-Fei Wei, Laurie A. Brewer, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, Charles E. Birse

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Abstract

The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Claims24

Dependent claims

An isolated antibody or fragment thereof that specifically binds to a polypeptide selected from the group consisting of:

(a) a polypeptide whose amino acid sequence consists of amino acid residues 1 to 508 of SEQ ID NO:139;
(b) a polypeptide whose amino acid sequence consists of a portion of SEQ ID NO:139, wherein said portion is at least 30 contiguous amino acid residues of SEQ ID NO:139;
and
(c) a polypeptide whose amino acid sequence consists of a portion of SEQ ID NO:139, wherein said portion is at least 50 contiguous amino acid residues of SEQ ID NO:139.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 10/849,979Filed 21 May 2004 · continuation
Priority: 12 May 1998
Published: US 2007/0172830 A126 Jul 2007
Granted: 24 Jul 2007
Term ends: Not estimatedThe source records don’t support an estimate.

Classification2 codes

C07K 14/47
From vertebrates: from mammals
C07K
Peptides

Family

Application60/085,093Us provisional application · filed 12 May 1998
Application60/085,094Us provisional application · filed 12 May 1998
Application60/085,105Us provisional application · filed 12 May 1998
Application60/085,180Us provisional application · filed 12 May 1998
Application60/085,927Us provisional application · filed 18 May 1998
Application60/085,906Us provisional application · filed 18 May 1998
Application60/085,920Us provisional application · filed 18 May 1998
Application60/085,924Us provisional application · filed 18 May 1998
Application60/085,922Us provisional application · filed 18 May 1998
Application60/085,923Us provisional application · filed 18 May 1998
Application60/085,921Us provisional application · filed 18 May 1998
Application60/085,925Us provisional application · filed 18 May 1998
Application60/085,928Us provisional application · filed 18 May 1998
PCT/US99/09847Parent of this continuation-in-part · filed 6 May 1999
Application09/437,658Parent of this continuation · filed 10 Nov 1999
Application60/231,846Us provisional application · filed 11 Sep 2000
Application09/892,877Parent of this continuation-in-part · filed 28 Jun 2001
Application09/948,783Parent of this continuation · filed 10 Sep 2001
Application09/948,783Parent of this continuation-in-part
Application09/892,877Parent of this continuation
Application09/437,658Parent of this continuation-in-part
US 2003/0077809 A1Published application
US 2003/0100051 A1Published application
US 2007/0172830 A1Published application
US 7,247,442 B1This patent

From the US filing history. Foreign family members aren’t listed.