Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or adult respiratory distress syndrome (ARDS) and infant respiratory distress syndrome (IRDS)

A composition for the treatment of Infant Respiratory Distress Syndrome (IRDS) or Adult Respiratory Distress Syndrome (ARDS) comprising

• a) a compound of formula I
• in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound;
• b) lung surfactant comprising a mixture of phospholipids;
• and
• c) lung surfactant protein, wherein the lung surfactant protein is a recombinant SP-C derivative which differs from human SP-C by replacement of the two cysteines (in positions 4 and 5) by phenylalanine and replacement of the methionine in position 32 by isoleucine.