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US 7,247,309 B2Granted
Coccidiosis vaccines
AssigneeIntervet International B.V.
InventorsArnoldus Nicolaas Vermeulen, Theodorus Petrus Maria Schetters
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Abstract
The present invention relates to coccidia strains and, in one embodiment, to microbiological cultures comprising such strains. In preferred embodiments, the coccidia strains are selected for tolerance to one group of coccidiostatic drugs, sensitivity to a second group of coccidiostatic drugs, and decreased proliferative capacity. Another embodiment of the invention relates to vaccines based on the coccidia strains according to the invention.
Claims4
A coccidiosis vaccine comprising a pharmaceutically acceptable carrier;
- and occysts from at least one strain of Eimeria coccidia having:
- a tolerance for at least one ionophoric drug,
- a sensitivity to at least one DNA synthesis inhibitor drug, and
- a decreased proliferative capacity,
- and wherein the at least one strain Eimeria coccidia is selected from the group consisting of Eimeria acervulina strain ACA-99112612, Eimeria tenella strain ACT-99112611, and Eimeria maxima strain ACVM-99112610.
2 more elements
A coccidiosis vaccine, comprising:
- a pharmaceutically acceptable carrier;
- and oocysts from at least two strains of Eimeria coccidia, said at least two strains of Eimeria coccidia being selected from the group consisting Eimeria acervulina strain ACA-99112612, Eimeria tenella strain ACT-99112611, and Eimeria maxima strain ACVM-99112610.
Dependencies are inferred from the claim text.