Method of the dosed application of a liquid onto a surface
AssigneeTechnische Universiteit Delft
InventorsRobert Moerman, Johannes Frank, Johannes Cornelis Maria Marijnissen
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Abstract
The invention relates to a method of the dosed application of a liquid onto to selected portion of the surface of a substrate (A) by means of spraying under the influence of an electric current. According to the invention the liquid is fed at a flow rate between 0.01 pl/s and 1 ml/s to a distal tip (3) of a capillary (1) having an inside diameter of less than 150 μm, wherein the distance between the distal tip and the surface (A) is less than 2 mm. Surprisingly it has been shown that it is possible in this manner to apply liquid to a restricted surface of a defined size.
Claims13
A method of electrospray deposition for the dosed application of a liquid onto a surface of a target substrate (for analysis) comprising:
- feeding the liquid to the distal tip of a capillary at a flow rate between 10 to 100 pl/s wherein the distal tip comprises an orifice directed toward the surface of the target substrate, and wherein the inside diameter of the distal tip of the capillary is 60 μm or less;
- and
- applying a voltage difference between the orifice or the liquid and a counter electrode or the target substrate until the desired amount of liquid has been applied to the surface, wherein the distance between the orifice and the surface of the target substrate is between 0.25 and 0.5 mm.
Dependencies are inferred from the claim text.