Bioabsorbable adhesive compounds and compositions
AssigneeTyco Healthcare Group LP
InventorMark S. Roby
Life of this patent
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Abstract
Bioabsorbable compounds which include a polyalkylene oxide backbone with two or more isocyanate substituents are useful as one component adhesives. Absorbable compositions useful as a two component adhesive contain a) a polyethylene oxide having two or more amine substituents with b) a bioabsorbable diisocyanate compound, or alternatively contain a) a polyethylene oxide having two or more isocyanate substituents with b) a bioabsorbable diamine compound, or, alternatively contain a) a bioabsorbable diisocyanate compound and b) a bioabsorbable diamine compound.
Claims6
A bioabsorbable composition comprising an amine-substituted polyalkylene glycol and a bioabsorbable isocyanate of the formula
- R′4-n—C—(R)n
- wherein the R′ groups can be the same or different at each occurrence and are each individually selected from the group consisting of —H and C1 to C8 alkylene groups, n is a number of from 2 to 4, and the R groups can be the same or different at each occurrence and are each individually selected from the group consisting of polyalkylene oxide groups and polyalkylene oxide groups substituted with at least one isocyanate group having the formula:
- -[A]n—NCO
- wherein A is a bioabsorbable group and n is from 1 to about 20,
- with the proviso that at least two of the R groups are polyalkylene oxide groups substituted with at least one isocyanate group.
A bioabsorbable composition comprising an amine-substituted polyalkylene glycol and a bioabsorbable isocyanate of the formula
- wherein the R groups are the same or different at each occurrence and are each individually selected from the group consisting of —H, C1 to C8 alkylene goups, polyalkylene oxide groups and polyalkylene oxide groups substituted with at least one isocyanate group having the formula:
- -[A]n—NCO
- wherein A is a bioabsorbable group and n is from 1 to about 20,
- with the proviso that at least two of the R groups are polyalkylene oxide groups substituted with at least one isocyanate group, and n is 2 to 6.
Dependencies are inferred from the claim text.