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OwnerCato T. Laurencin, Lakshmi Sreedharan Nair +5inventors
InventorsCato T. Laurencin, Lakshmi Sreedharan Nair, Subhabrata Bhattacharyya, Harry R. Allcock, Jared D. Bender, Paul W. Brown, Yaser E. Greish
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Polymeric nanofibers have been developed which are useful in a variety of medical and other applications, such as filtration devices, medical prosthesis, scaffolds for tissue engineering, wound dressings, controlled drug delivery systems, cosmetic skin masks, and protective clothing. These can be formed of any of a variety of different polymers, either non-degradable or degradable. In a preferred embodiment demonstrated in the following examples, nanofibers are formed of biodegradable and non biodegradable polyphosphazenes, their blends with other polyphosphazenes or with organic, inorganic/organometallic polymers as well as composite nanofibers of polyphosphazenes with nanosized particles such as hydroxyapatites.
A device comprising biocompatible polymeric nanofibers having a diameter of between 100 and 1000 nm, wherein the device is selected from the group consisting of a medical device, sutures, drug delivery device, matrix or scaffold for tissue engineering, repair or regeneration device, medical prosthesis, or cosmetic skin mask, and wherein the polymer has the formula shown below:
Dependencies are inferred from the claim text.