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AssigneeTakeda Pharmaceutical Company Limited
InventorsTsuyoshi Maekawa, Jun Kunitomo, Hiroyuki Odaka, Hiroyuki Kimura
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The present invention provides a retinoid-related receptor (except retinoic acid receptors) function regulating agent comprising a compound represented by the formula: wherein one of R1 and R2 is an optionally substituted monocyclic aromatic hydrocarbon group or an optionally substituted monocyclic aromatic heterocyclic group containing one heteroatom, and the other is a hydrogen atom and the like; B is a 5- or 6-membered heterocycle (except 1,3-azole); A is an optionally substituted aromatic hydrocarbon group or an optionally substituted aromatic heterocyclic group; and R3 is a hydrogen atom and the like, or a salt thereof, which is useful as an agent for the prophylaxis or treatment of diabetes mellitus, hyperlipidemia, impaired glucose tolerance or the like.
A method for the treatment of obesity in a mammal, which comprises administering, to the mammal, a peroxisome proliferator-activated receptor transcriptional activity promoter which is non-binding to peroxisome proliferator-activated receptors, wherein the peroxisome proliferator-activated receptor transcriptional activity promoter is a compound represented by the formula:
Dependencies are inferred from the claim text.