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US 7,223,567 B2Granted
Mutant E. coli strain with increased succinic acid production
AssigneeRice University
InventorsSan Ka-Yiu, George N. Bennett, Ailen Sanchez
Life of this patent
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Abstract
The invention relates to a mutant strain of bacteria, which either lacks or contains mutant genes for several key metabolic enzymes, and which produces high amounts of succinic acid under anaerobic conditions.
Claims9
A genetically engineered bacterial strain wherein said bacteria comprise:
- a) a disruption of ldhA;
- b) a disruption of adhE;
- and
- c) a disruption of ack-pta.
1 more element
Dependencies are inferred from the claim text.