Conjugated linoleic acid isomerase and a process for the production of conjugated linoleic acid
AssigneeTeagasc Dairy Products Research Centre
InventorsCatherine Stanton, R. Paul Ross, Oskar Zelder, Bruno Kaesler
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Abstract
The present invention relates to a process for the production of conjugated linoleic acid and a process for the production of triglycerides with an increased content of conjugated linoleic acid. Moreover, the invention relates to a nucleic acid sequence; a nucleic acid construct, a vector and transgenic organisms comprising at least one nucleic acid sequence or one nucleic acid construct which encodes a polypeptide with conjugated linoleic isomerase activity. Furthermore, the invention relates to the use of a microorganism of the genus Bifidobacterium as a probiotic.
Claims17
An isolated nucleic acid molecule which encodes a polypeptide with conjugated linoleic acid isomerase activity, or the full complement thereof, selected from the group consisting of:
- a) a nucleic acid molecule comprising the nucleotide sequence set forth in SEQ ID NO:
- 1,
- b) a nucleic acid molecule comprising a nucleotide sequence which encodes a polypeptide sequence comprising the amino acid sequence as set forth in SEQ ID NO:2,
- c) a nucleic acid molecule comprising a nucleotide sequence which is a derivative of the nucleic acid sequence shown in SEQ ID NO:
- 1, which encodes a polypeptide having at least 98% identity to the entire amino acid sequence as set forth in SEQ ID NO:2 without substantially reducing the enzymatic activity of the polypeptide;
- and
- d) a nucleic acid molecule comprising a nucleotide sequence which is at least 95% identical to the entire nucleotide sequence set forth in SEQ ID NO:1 and encodes a polypeptide having conjugated linoleic acid isomerase activity.
Dependencies are inferred from the claim text.