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AssigneesBio Merieux, Centre National De La Recherche Scientifique
InventorsAbdelhamid Elaissari, Franck Montagne, Eric Bosc, Christian Pichot, Bernard Mandrand, Jérôme Bibette, Olivier Mondain-Monval
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The invention relates to composite particles comprising a hydrophobic polymer core and inorganic nanoparticles. Said hydrophobic polymer forms a polymer matrix inside which the inorganic nanoparticles are stabilized and distributed in a relatively homogenous manner. Said particles are at least partially surrounded by an amphophilic copolymer comprising a hydrophobic part and a hydrophilic part, said hydrophobic part being at least partially immobilized in the polymer matrix. The inventor also relates to the preparation method thereof, the conjugates comprising such particles and a ligand and the use of same in reactants and therapeutic compositions.
A composite particle comprising a core made of a hydrophobic polymer and inorganic nanoparticles, said hydrophobic polymer constituting a polymer matrix within which the inorganic nanoparticles are stabilized and distributed homogeneously, said particle being characterized in that it is at least partially surrounded by an amphiphilic copolymer comprising a hydrophobic part and a hydrophilic part, the hydrophobic part of which is at least partially immobilized on or in said polymer matrix.
Dependencies are inferred from the claim text.