Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
AssigneeChiron Corporation
InventorsJan zur Megede, Susan Barnett
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Abstract
The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Uses of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of these polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof.
Claims47
An expression cassette, comprising a polynucleotide sequence encoding a polypeptide including an immunogenic HIV Gag polypeptide, wherein the polynucleotide sequence encoding said immunogenic HIV Gag polypeptide comprises a sequence having at least 90% sequence identity to SEQ ID NO:9.
Dependencies are inferred from the claim text.