Porous delivery scaffold and method
AssigneeDePuy Products, Inc.
InventorsPrasanna Malaviya, Herbert E. Schwartz, Pamela L. Plouhar, Janine M. Orban
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Abstract
A method of making an implantable scaffold for repairing damaged or diseased tissue includes the step of suspending pieces of an extracellular matrix material in a liquid. The extracellular matrix material and the liquid are formed into a mass. The liquid is subsequently driven off so as to form interstices in the mass. The scaffold may further comprise biological agents that promote tissue repair and healing. Porous implantable scaffolds fabricated by such a method are also disclosed.
Claims15
A method of making an implantable scaffold for repairing or regenerating body tissue, the method comprising the steps of:
- comminuting naturally occurring extracellular matrix material in the presence of a liquid to form a slurry comprising intertwined, ribbon-like, cohesive pieces of the naturally occurring extracellular matrix material suspended in the liquid;
- freeze-drying the intertwined, ribbon-like, cohesive pieces of naturally occurring extracellular matrix material and the liquid to form a porous structure;
- and
- incorporating at least one biological agent into the freeze-dried extracellular matrix material.
Dependencies are inferred from the claim text.