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AssigneeGrisotech S.A.
InventorsRolando Wyss, Bernad Bizzini, Ivo Volpato
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The present invention relates to complexes consisting of immunoglobulins and polysaccharides for oral and transmucosal use. The polysaccharides comprised in the complexes according to the invention form an envelope which protects and carries immunoglobulins allowing their systemic absorption through the gastric and mucosal district. Immunoglobulins have a different specificity depending on the required therapeutic effect. They are used in passive immunoprophylaxis for the prevention or therapy of infections caused by pathogenic agents such as virus, bacteria, parasites, or they are used in the modulation of endogenous bio-chemical balances, or in the detoxification from drugs of abuse, medicines, toxins.
A therapeutic method for detoxifying an animal or a human subject in need of being detoxified from an exogenous substance comprising administering to said subject a therapeutically effective amount of a pharmaceutical composition consisting of:
A therapeutic method for regulating the levels of an endogenous substances in an animal or human subject comprising administering to said subject a therapeutically effective amount of a pharmaceutical composition consisting of immunoglobulins having specificity for said endogenous substance as the active ingredient and a polysaccharide selected from the group consisting of chitosanes and alginates, in combination with suitable excipients and diluents, wherein in said pharmaceutical composition the polysaccharidic molecules are neither chemically cross-linked to the immunoglobulins nor to each other.
A method for detoxifying an animal subject so as to ensure decontamination of the final product comprising administering to said subject a therapeutically effective amount of a composition consisting of:
Dependencies are inferred from the claim text.