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US 7,169,751 B2Granted
Method of identifying a compound capable of treating a pain or a painful disorder
AssigneeBayer HealthCare LLC
InventorsInmaculada Silos-Santiago, Venkateswarlu Karicheti, Scott D. Eliasof
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Abstract
We claim a methods for identifying a compound capable of treating a pain or a painful disorder state comprising combining the test compound with the polypeptide of SEQ ID NO:2, and detecting binding of said test compound to said polypeptide thereby identifying a compound that binds to said polypeptide.
Claims7
A method for identifying a compound capable of treating a pain or a painful disorder, comprising:
- a) combining a compound to be tested with a polypeptide selected from the group consisting of:
- i) a polypeptide comprising the amino acid sequence of SEQ ID NO:2;
- and
- ii) a polypeptide which is encoded by a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:1;
- under conditions suitable for binding of the test compound to the polypeptide;
- and
- b) detecting binding of the test compound to the polypeptide to thereby identify a compound which binds to the polypeptide,
- thereby identifying a compound capable of treating a pain or a painful disorder.
5 more elements
Dependencies are inferred from the claim text.