Uses of aldose-1-epimerase (mutarotase) for diagnosis and therapy of inflammatory diseases and sepsis
AssigneeB.R.A.H.M.S GmbH
InventorsAndreas Bergmann, Joachim Struck, Monika Ühlein
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Abstract
Uses of aldose 1-epimerase (SEQ ID NO:3) from body fluids or body tissues in human and veterinary medicine as a marker peptide for diagnosis, for prognosis of the course and for monitoring of the course of inflammations and infections and/or as a target for therapeutically influencing the course of inflammations and/or infections.
Claims8
A method of differential early diagnosis and detection for the prognosis of, and therapy-accompanying assessment of the course of sepsis and severe infection in a patient in need thereof, the method comprising providing a biological fluid or a tissue sample from said patient, detecting and/or determining the presence and/or amount of human aldose 1-epimerase (A1E;
- SEQ ID #3) in the biological fluid or tissue sample from said patient, determining the presence, severity and course of the sepsis and severe infection, and evaluating the success of a therapy of the sepsis or severe infection in said patient.
Dependencies are inferred from the claim text.