Method for the production of borosilicate glass with a surface suitable for modification glass obtained according to said method and the use thereof

A borosilicate glass with an easily modified surface, said easily modified surface having reactive SiOH groups thereon, wherein said borosilicate glass is made by a method comprising the steps of:

• a) making a glass melt comprising a borosilicate glass;
• and
• b) dissolving at least 30 mMol of water in said glass melt per liter of said glass melt;
• wherein said boroslilcate glass comprises from 70 to 87 percent by weight of SiO2, from 7 to 15 percent by weight of B2O3, from 0 to 8 percent by weight of Al2O3, from 0 to 8 percent by weight of Na2O, from 0 to 8 percent by weight of K2O and optionally from 0 to 8 percent by weight of additional optional components.

A substrate for chemically covalent immobilization of reactive substances, said substrate comprising a borosilicate glass with an easily modified surface, said easily modified surface having reactive SiOH groups thereon, wherein said borosilicate glass is made by a method comprising the steps of:

• a) making a glass melt comprising a borosilicate glass;
• and
• b) dissolving at least 30 mMol of water in said glass melt per liter of said glass melt;
• wherein said borosilicate glass comprises from 70 to 87 percent by weight of SiO2, from 7 to 15 percent by weight of B2O3, from 0 to 8 percent by weight of Al2O3, from 0 to 8 percent by weight of Na2O, from 0 to 8 percent by weight of K2O and optionally from 0 to 5 percent by weight of additional optional components.