US 7,150,995 B2 · Methods and systems for point of care bodily fluid analysis

Abstract

The invention provides a system for quantitative measurement of percent glycated hemoglobin as hemoglobin A1c in whole blood having extended shelf life at room temperature. The system comprising a blood dilution solution and a device adapted for receiving at least a portion of diluted blood solution, for contacting the blood solution with a dry reagent system, for detecting a change in the reagent system and for providing an indication of the analytical result to the user, and the extended shelf life and the elimination of a requirement for refrigeration for storage is achieved by having the blood dilution solution which comprises a first surfactant for hemolysis and a second surfactant for stability. The system of this invention is useful in other analysis kits and systems as well.

Claims12

Dependent claims

A system for quantitative measurement of percent glycated hemoglobin in whole blood, comprising:

a blood dilution solution;
a dry immunoassay reagent system;
and
a device adapted for:
receiving at least a portion of diluted blood solution;
contacting the blood solution with the dry immunoassay reagent system for detecting a change in the reagent system;
and
providing an indication of the analytical result to the user;
wherein the blood dilution solution comprises N-tetradecyl-N,N-dimetyl-3 -ammonio-1-propanesulfonate, and a nonionic surfactant selected from the group consisting of an ethoxylated acetylenic glycol polymer, and a block copolymer of ethylene oxide and propylene oxide;
wherein the blood dilution solution is not in contact with the dry immunoassay reagent system during storage.

7 more elements

Dependencies are inferred from the claim text.

Methods and systems for point of care bodily fluid analysis

Life of this patent

Methods and systems for point of care bodily fluid analysis

Life of this patent

Abstract

Claims12