Hydrogel composition for measuring glucose flux
AssigneeAnimas Technologies, LLC
InventorsJanet A. Tamada, Michael J. Tierney, Stephen C. Williams
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Abstract
The present invention relates to compositions for use in analyte monitoring devices. These compositions are useful to increase the flux of analyte across skin, tissue or mucosal surfaces. The compositions include hydrogels and collection reservoir systems comprising ionically conductive materials. The present invention also includes methods of making/manufacturing hydrogels or collection reservoir systems, collection assemblies comprising the hydrogels, electrode assemblies in combination with the hydrogels or collection reservoir systems, and methods of using the same.
Claims21
A hydrogel composition for measuring glucose flux, said hydrogel composition comprising:
- a hydrophilic compound which forms a gel in the presence of water, an electrolyte, a phosphate buffer present at a concentration of between about 125 mM and about 500 mM, and a pH of between about pH 6.5 to about pH 8.5, wherein the glucose flux into the hydrogel is at least 0.65 nmol/cm2·hr.
Dependencies are inferred from the claim text.