Method of making an anti-infective composition for treating oral infections
AssigneeVentria Bioscience
InventorsNing Huang, Jianmin Huang, Delia R. Bethell
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Abstract
This invention concerns a method of making an anti-infective composition for oral administration using an agent selected from the group consisting of lactoferrin protein and lysozyme protein. The method comprises three steps. The nucleic acid, which encodes a lactoferrin or lysozyme protein, is expressed in a monocot seed. The protein is isolated from the seed. This protein isolation compromises greater than 3% of the total soluble protein in the monocot seed. The protein is then formulated for oral administration.
Claims11
A method of making an anti-infective composition suitable for oral administration comprising an agent including at least one protein selected from the group consisting of lactoferrin protein and lysozyme protein, comprising the steps of:
- a) expressing a nucleic acid encoding at least one protein selected from the group consisting of human lactoferrin protein and human lysozyme protein in a monocot seed;
- b) isolating the at least one protein from the seed, wherein the at least one protein comprises about 3% or greater of the total soluble protein in the seed;
- c) combining the at least one protein with a pharmaceutically acceptable carrier or diluent to provide a composition suitable for oral administration.
Dependencies are inferred from the claim text.