Nanosensors
AssigneePresident and Fellows of Harvard College
InventorsCharles M. Lieber, Hongkun Park, Qingqiao Wei, Yi Cui, Wenjie Liang
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Abstract
Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes. They can be arranged in crossbar arrays using chemically patterned surfaces for direction, via chemical vapor deposition. Chemical vapor deposition also can be used to form nanotubes in arrays in the presence of directing electric fields, optionally in combination with self-assembled monolayer patterns. Bistable devices are described.
Claims74
An article for detecting an analyte by allowing the analyte to bind to a reaction entity selected to interact with the analyte, the article comprising:
- a sample exposure region, a semiconductor nanowire deposited after growth proximal the sample exposure region, at least a portion of which is addressable by a sample in the sample exposure region, and a chemical or biological reaction entity positioned relative to the nanowire such that an interaction between the reaction entity and an analyte in the sample causes a detectable change in a property of the nanowire, whereby the detectable change in the property of the nanowire can be determined to detect the analyte.
An article for detecting an analyte by allowing the analyte to bind to a reaction entity selected to interact with the analyte, the article comprising:
- a sample exposure region, a semiconductor nanowire, at least a portion of which is addressable by a sample in the sample exposure region, a chemical or biological reaction entity positioned relative to the nanowire such that an interaction between the reaction entity and an analyte in the sample causes a detectable change in a property of the nanowire, and a substrate having a composition different from the nanowire, whereby the detectable change in the property of the nanowire can be determined to detect the analyte.
Dependencies are inferred from the claim text.