Modeling viscoelastic torsional properties of osteons
OwnerMaria-Grazia Ascenzi, John Michael Kaboinventors
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Abstract
The present invention provides a geometric/material computer model of hierarchical bone based upon the viscoelastic properties of longitudinal and alternate osteons. The viscoelastic properties of osteons include, for example, mechanical properties and osteon content of various components such as collagen, mucopolysacharides, hydroxyapatite, osteocytes and osteoblasts. The invention also provides a method for preparing such a model.
Claims37
A system for modeling macrostructural characteristics of a bone comprising:
- a first hierarchical order comprising at least one macroscopic region of the bone,
- a second hierarchical order comprising at least one empirically-derived non-homogeneous second order component representing one or more osteons, trabeculae, or lamellae within the macroscopic region, and
- a viscoelastic property correlated with at least one second order component, and
- wherein the second order components are used to determine properties of the first hierarchical order region, and
- wherein a property of the first hierarchical order region is determined based on the viscoelastic property of the second order component.
A method of producing a model of bone, comprising the steps of:
- a) specifying a first hierarchical order macroscopic region of a selected bone;
- b) dividing the macroscopic region into a finite number of elements of second hierarchical order, each element representing an empirically-derived non-homogeneous second order component comprising one or more osteons, trabeculae, or lamellae;
- c) assigning a viscoelastic property to at least one second order component and
- d) determining a property of the first hierarchical order macroscopic region of the selected bone based on the viscoelastic property of the second order components.
A method of producing a model of a bone comprising the steps of:
- a) specifying a first hierarchical order macroscopic region of a selected bone;
- b) dividing the macroscopic region into a finite number of elements of second hierarchical order, each element representing an empirically-derived non-homogeneous second order component comprising one or more alternate and extinct osteons;
- c) assigning a viscoelastic property to at least one second order component, wherein the viscoelastic property comprises at least one parameter selected from the group consisting of collagen content, mucopolysaccharide content, hydroxyapatite content, osteocyte content, osteoblast content, and content of porosity fluids;
- and
- d) determining a viscoelastic property of the first hierarchical order macroscopic region of the selected bone based on the viscoelastic properties of the second order components.
Dependencies are inferred from the claim text.