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US 7,126,025 B2Granted
Synthesis of 4-(amino)-2-butenoyl chlorides and their use in the preparation of 3-cyano quinolines
AssigneeWyeth
InventorsJohn Leo Considine, Sylvain Daigneault, Warren Chew, Silvio Iera, Scott Mason Duncan, Jianxin Ren
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Abstract
This invention provides a compound of Formula (I): wherein S1 and S2 are each independently, hydrogen, alkyl, alkenyl, alkynyl, aralkyl, substituted or unsubstituted aryl, and S1 and S2 together with the nitrogen to which they are attached form a nitrogen containing heteroaryl and a pharmaceutically acceptable salt thereof; a method of preparing the compound of Formula (I), and use of the compound of Formula (I) in the preparation of 3-cyano quinolines.
Claims12
A compound of Formula (I):
- wherein
- S1 and S2 are each independently, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, aralkyl, substituted or unsubstituted aryl or heteroaryl, or S1 and S2 together with the nitrogen to which they are attached form a nitrogen containing heteroaryl or cycloheteroalkyl;
- or
- an acid addition salt thereof.
1 more element
Dependencies are inferred from the claim text.