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US 7,126,004 B2Granted
Thiazoline acid derivatives
AssigneeUniversity of Florida Research Foundation, Inc.
InventorRaymond J. Bergeron
Life of this patent
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Abstract
The present invention relates to novel thiazoline acids and derivatives thereof useful as chelators of trivalent metals in therapeutic applications. For example, the thiazoline acid derivatives are useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals.
Claims16
A method of preparing a compound of the formula:
- and salts thereof with a pharmaceutically acceptable acid, comprising:
- a) reacting a first reagent of the formula:
- wherein the hydroxyl groups of the first reagent are optionally protected by protecting groups, with a second reagent of the formula:
- or a salt thereof with a pharmaceutically acceptable acid;
- and
- b) removing the protecting groups, if present.
3 more elements
Dependencies are inferred from the claim text.