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US 7,125,987 B2Granted
Process for the preparation of oxcarbazepine and related intermediates
AssigneeApotex Pharmachem Inc.
InventorsDaqing Che, Nadia Corelli-Rennie, Bhaskar Reddy Guntoori, Jodi Faught
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Abstract
A process for preparing Oxcarbazepine III comprising: a) reacting oximinostilbene IV with chlorosulfonyl isocyanate in an inert organic solvent and isolating compound V b) hydrolyzing compound V to form crude Oxcarbazepine III c) purifying oxcarbazepine.
Claims37
A process for preparing Oxcarbazepine III
- comprising:
- a) reacting oximinostilbene IV
- with chlorosulfonyl isocyanate in an inert organic solvent and isolating compound V
- b) hydrolyzing compound V to form crude Oxcarbazepine III
- c) purifying oxcarbazepine.
2 more elements
A process for preparing compound IV
- comprising hydrolysis of compound I
- with an aqueous inorganic acid in a water-miscible organic solvent.
Dependencies are inferred from the claim text.